FIGURE

Figure 1

ID

ZDB-FIG-240327-21

Publication

Daurat et al., 2024 - Engineered therapeutic antibodies with mannose 6-phosphate analogues as a tool to degrade extracellular proteins

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Figure 1

Characterization of Infliximab (IFX) and Bevacizumab (BVZ) before and after AMFA grafting. Analysis of IFX and IFX-AMFA1 (A) and BVZ, BVZ-AMFA1 and BVZ-AMFA2 (B) under non reducing and reducing conditions of SDS-PAGE followed by Coomassie blue staining or by Western blotting using anti-human IgG or anti-AMFA antibodies. Affinity of IFX and IFX-AMFA1 for TNF-α (C), affinity of BVZ, BVZ-AMFA1 and BVZ-AMFA2 for VEGF (D) and the M6PR (E). Binding assays were performed by ELISA method. Results of two independent experiments are presented as mean ± SD of absorbance values at 450 nm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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