FIGURE

Fig. 1

ID

ZDB-FIG-240318-51

Publication

Nwagbo et al., 2024 - Elovl4b Knockout Zebrafish as a Model for Ocular Very-Long-Chain Polyunsaturated Fatty Acid Deficiency

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Fig. 1

VLC-PUFA biosynthetic pathways in mammals and zebrafish. Comparison of the VLC-PUFA biosynthetic pathways from linoleic (18:2n-6) and α-linolenic (18:3n-3) acid precursors of zebrafish and mammalian vertebrates (adapted from Refs. (10) and (13)). Large dashed black arrows represent the desaturation steps, small dashed arrows represent the β-oxidation steps, and solid arrows represent the elongation steps. AA, arachidonic acid; ALA, α-linolenic acid; LA, linoleic acid. Color key: red text: mammalian (human and murine) orthologues, blue text: zebrafish orthologues, and brown text and arrows: pathway presumed but not confirmed in zebrafish.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Lipid Res.