FIGURE

Fig. 6

ID
ZDB-FIG-240222-139
Publication
Yang et al., 2023 - nkx2.3 is responsible for posterior pharyngeal cartilage formation by inhibiting Fgf signaling
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Fig. 6

Knockdown of nkx2.3 increased Fgf signal and fgf8 overexpression mimic the phenotype of nkx2.3 morphants. (A) Expression pattern of fgf3 and fgf8 in nkx2.3 morphants detected by ISH at 36 hpf. i, isthmus; os, optic stalk; pvh, posterior-ventral hypothalamus; ep, endodermal pouches; mhb, midbrain-hindbrain boundary; ah, adenohypophysis. (B) Morphology of embryos with overexpressed fgf8. Scale bars: 200 ?m. (C) Alcian blue staining of embryos in which fgf8 was overexpressed. Scale bars: 100 ?m. (D) Immunostaining of Col2a proteins in fgf8 transgenic embryos at 4 dpf. Scale bars: 10 ?m.

Expression Data
Genes:
Fish:
Knockdown Reagent:
Anatomical Term:
Stage: Prim-25

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Condition:
Knockdown Reagent:
Observed In: (all 9)
Stage Range: Prim-25 to High-pec

Phenotype Detail
Acknowledgments
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