FIGURE

Fig. 1

ID

ZDB-FIG-240222-134

Publication

Yang et al., 2023 - nkx2.3 is responsible for posterior pharyngeal cartilage formation by inhibiting Fgf signaling

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Fig. 1

Malformation of pharyngeal cartilages in nkx2.3 morphants. (A) Morphology of WT embryos injected with nkx2.3 MOs at indicated stages. Scale bars, 200 ?m. (B) Morphology of p53 mutant embryos injected with nkx2.3 MOs at 4 dpf. Scale bars, 200 ?m. (C) Detection of craniofacial cartilages formation using Alcian blue staining. The cartilages were shown anterior to the left and included the ceratobranchial (cb), ceratohyal (ch), Meckel's cartilage (m), basibranchial (bb), basihyal (bh), hypobranchial(hb), and palatoquadrate (pq) cartilages. Scale bars, 100 ?m.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	tp53^zdf1/zdf1 (TU) TU + MO1-nkx2.3 TU + MO2-nkx2.3 tp53^zdf1/zdf1 + MO1-nkx2.3 (TU) tp53^zdf1/zdf1 + MO2-nkx2.3 (TU)
Knockdown Reagents:	MO1-nkx2.3 MO2-nkx2.3
Observed In:	ceratobranchial cartilage ceratohyal cartilage epibranchial cartilage head hyosymplectic cartilage hypobranchial cartilage mandibular arch skeleton Meckel's cartilage palatoquadrate cartilage
Stage:	Day 4

Phenotype Detail

Acknowledgments

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