FIGURE

Fig. 17

ID

ZDB-FIG-240130-33

Publication

Mi et al., 2023 - Stimulation of liver fibrosis by N2 neutrophils in Wilson's disease

Other Figures

All Figure Page

Back to All Figure Page

Fig. 17

STAT3 is highly increased in liver neutrophils in ATP7B-KO mice. (A) Formalin-fixed mouse liver tissue sections from STATTIC-treated or vehicle-treated wild-type and ATP7B-KO mice were subjected to immunofluorescence staining of anti-pSTAT3 and anti-Ly6G. Representative images of pSTAT3 (green), Ly6G (red), and nuclei (blue) are shown. Arrows indicate pSTAT3-positive liver neutrophils. Scale bar: 40 ?m. (B) qPCR of mRNA levels of Stat3 in liver neutrophils isolated from wild-type and ATP7B-KO mice upon STATTIC or vehicle treatment. n = 3 sets of liver neutrophils pooled from 2?3 mice. ??P < .01. DAPI, 4?,6-diamidino-2-phenylindole; WT, wild-type.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cell Mol Gastroenterol Hepatol