FIGURE

Figure 4

ID

ZDB-FIG-231115-18

Publication

Li et al., 2023 - Stanniocalcin 1a regulates organismal calcium balance and survival by suppressing Trpv6 expression and inhibiting IGF signaling in zebrafish

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Figure 4

Loss of Stc1a results in abnormal calcium deposits in a Trpv6-depndent manner. (A) Larvae (3 dpf) of the indicated genotypes treated with or without 10 μg/L CdCl₂ for 2 days. They were subjected to Alizarin red staining at 5 dpf. Representative images are shown. Note the ectopic calcified structures in the yolk sac region (arrow) and kidney stones (arrow heads) in the mutant fish. Scale bar = 0.5 mm. (B) Alizarin red staining analysis of 7 dpf zebrafish larvae of the indicated genotypes. Representative images are shown. Note the ectopic calcified structures in the yolk sac region (arrow) and kidney stones (arrow heads) in the mutant fish. Scale bar = 0.2 mm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	stc1l^mi610/mi610 trpv6^mi604/mi604; stc1l^mi610/mi610
Condition:	chemical treatment by environment: cadmium dichloride
Observed In:	kidney anatomical structure yolk syncytial layer
Stage Range:	Day 5 to Days 7-13

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Endocrinol (Lausanne)