FIGURE

Figure 7

ID

ZDB-FIG-230428-22

Publication

Frantz et al., 2023 - Pigment cell progenitor heterogeneity and reiteration of developmental signaling underlie melanocyte regeneration in zebrafish

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Figure 7

aox5 expression predicts in vivo progenitor cell fate.

(A) Representative image of progenitors expressing different levels of aox5 promoter-driven PALM-EGFP. mitfa⁺aox5^hi (arrowhead), mitfa⁺aox5^lo (arrow). Scale bar = 50 µm. (B) Quantification of PALM-EGFP fluorescence intensity indicates groups of progenitors that express lower and higher levels of aox5. Mean pixel intensity per area; intensity values log normalized. n = 73 cells from 5 animals. (C) Images of an mitfa⁺aox5^hi cell that underwent mitosis following melanocyte destruction. Scale bar = 30 µm. (D) Comparison of aox5 intensity in cells that underwent symmetric divisions or remained inactive. Mean pixel intensity per area; intensity values log normalized. n = 17 cells from 5 animals. p values calculated by Student’s t-test, ***p < 0.001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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