FIGURE

Fig. 13

ID

ZDB-FIG-230207-41

Publication

Li et al., 2022 - Erianin Controls Collagen-Mediated Retinal Angiogenesis via the RhoA/ROCK1 Signaling Pathway Induced by the alpha2/beta1 Integrin-Collagen Interaction

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Fig. 13

Effects of erianin on the RhoA/ROCK1 pathway in vitro. (A) The mRNA levels of RHOA, ROCK1, and MYPT1 in HRVECs exposed to normoxia, CoCl₂, or erianin at various concentrations. (B) (B–I) Protein levels of GTP-RhoA, ROCK1, and p-MYPT1 in HRVECs exposed to normoxia, CoCl₂, or erianin at various concentrations. (B–II) Quantitative analysis of GTP-RhoA, ROCK1, and p-MYPT1; the results are presented as percentages of the normoxia group. * Significant difference between samples (paired t-test, P values < 0.05); ^# Comparison with the collagen group of CoCl₂-incubated cells without erianin treatment (paired t-test, P values < 0.05); † Comparison with noncollagen group of normoxia cells without erianin treatment (independent sample t-test, P values < 0.05).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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