FIGURE

Fig. 4

ID

ZDB-FIG-230207-32

Publication

Li et al., 2022 - Erianin Controls Collagen-Mediated Retinal Angiogenesis via the RhoA/ROCK1 Signaling Pathway Induced by the alpha2/beta1 Integrin-Collagen Interaction

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Fig. 4

Effect of erianin on HRVEC migration. (A) Collagen-cultured hypoxic HRVEC migration was evaluated by Transwell assay (100 ×). (Ⅰ) Cells without CoCl₂ and erianin exposure; (Ⅱ) cells with CoCl₂ and without erianin exposure; hypoxic cells exposed to erianin at various concentrations of 10 nM (Ⅲ), 25 nM (Ⅳ), 50 nM (Ⅴ), and 100 nM (Ⅵ). (B) Cell migration of noncollagen-cultured HRVECs evaluated by wound healing assays (100 ×). (C) Comparison of the inhibition rate of cell migration among collagen groups and among noncollagen groups. The normoxia group was set as the control at 100%. * Significant difference between samples (paired t-test, P values < 0.05); ^# Significant difference compared with CoCl₂-incubated cells without erianin treatment (paired t-test, P values < 0.05).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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