FIGURE

Fig. 4

ID

ZDB-FIG-230207-32

Publication

Li et al., 2022 - Erianin Controls Collagen-Mediated Retinal Angiogenesis via the RhoA/ROCK1 Signaling Pathway Induced by the alpha2/beta1 Integrin-Collagen Interaction

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Fig. 4

Effect of erianin on HRVEC migration. (A) Collagen-cultured hypoxic HRVEC migration was evaluated by Transwell assay (100 �). (?) Cells without CoCl₂ and erianin exposure; (?) cells with CoCl₂ and without erianin exposure; hypoxic cells exposed to erianin at various concentrations of 10 nM (?), 25 nM (?), 50 nM (?), and 100 nM (?). (B) Cell migration of noncollagen-cultured HRVECs evaluated by wound healing assays (100 �). (C) Comparison of the inhibition rate of cell migration among collagen groups and among noncollagen groups. The normoxia group was set as the control at 100%. * Significant difference between samples (paired t-test, P values < 0.05); ^# Significant difference compared with CoCl₂-incubated cells without erianin treatment (paired t-test, P values < 0.05).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Invest. Ophthalmol. Vis. Sci.