FIGURE

Figure 7

ID

ZDB-FIG-230122-71

Publication

Shi et al., 2023 - Single-cell transcriptomic profiling of the zebrafish inner ear reveals molecularly distinct hair cell and supporting cell subtypes

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Figure 7

Distinct markers separate macula and crista hair cells.

(A) Feature plots showing marker genes enriched in organ-specific subsets of inner ear hair cells: cabp5b, skor2, and loxhd1b. (B–D) HCR in situs in 5 dpf myo6b:GFP fish show expression of (B) cabp5b in crista but not macula hair cells, (C) skor2 in the utricle only, and (D) loxhd1b in the saccule, as well as lateral line neuromast hair cells. Each set of images represents an orthogonal projection of one z-stack split into cristae (lateral) and macular (medial) slices. ac: anterior crista, lc: lateral crista, nm: neuromast, pc: posterior crista, s: saccule, u: utricle. Scale bar = 20 μm.

Expression Data

Genes:	cabp5b loxhd1b skor2
Fish:	w186Tg
Anatomical Terms:	anterior crista auditory receptor cell lateral crista auditory receptor cell neuromast hair cell posterior crista auditory receptor cell saccule auditory receptor cell utricle auditory receptor cell
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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