Gene

loxhd1b

ID
ZDB-GENE-081104-370
Name
lipoxygenase homology PLAT domains 1b
Symbol
loxhd1b Nomenclature History
Previous Names
  • si:dkey-210e6.2
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have catalase activity and heme binding activity. Predicted to be involved in oxidation-reduction process. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy; autosomal recessive nonsyndromic deafness 77; and orofacial cleft. Orthologous to human LOXHD1 (lipoxygenase homology domains 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from Shi et al., 2023
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With loxhd1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive nonsyndromic deafness 77 Alliance Deafness, autosomal recessive 77 613079
Associated With loxhd1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001024 PLAT/LH2 domain
Family IPR052970 Inner ear hair cell lipoxygenase homology domain-containing protein
Homologous_superfamily IPR036392 PLAT/LH2 domain superfamily
Domain Details Per Protein
Protein Length Inner ear hair cell lipoxygenase homology domain-containing protein PLAT/LH2 domain PLAT/LH2 domain superfamily
UniProtKB:A0A8M1QHF7 2268
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA loxhd1b-201 (1) Ensembl 6,884 nt
mRNA loxhd1b-202 (1) Ensembl 6,060 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations