Gene

skor2

ID
ZDB-GENE-060825-57
Name
SKI family transcriptional corepressor 2
Symbol
skor2 Nomenclature History
Previous Names
  • skor2 (1)
  • zgc:153395
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and SMAD binding activity. Predicted to be involved in negative regulation of BMP signaling pathway and negative regulation of transcription by RNA polymerase II. Predicted to localize to nucleus and transcription regulator complex. Is expressed in spinal cord interneuron. Orthologous to human SKOR2 (SKI family transcriptional corepressor 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With skor2 Human Ortholog
No data available
Associated With skor2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003380 SKI/SNO/DAC domain
Domain IPR014890 c-SKI SMAD4-binding domain
Family IPR023216 Transcription regulator SKI/SnoN
Homologous_superfamily IPR009061 Putative DNA-binding domain superfamily
Homologous_superfamily IPR010919 SAND-like domain superfamily
Homologous_superfamily IPR037000 Ski-like, DNA-binding domain superfamily
Domain Details Per Protein
Protein Length c-SKI SMAD4-binding domain Putative DNA-binding domain superfamily SAND-like domain superfamily Ski-like, DNA-binding domain superfamily SKI/SNO/DAC domain Transcription regulator SKI/SnoN
UniProtKB:Q0P456 255
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations