Gene
skor2
- ID
- ZDB-GENE-060825-57
- Name
- SKI family transcriptional corepressor 2
- Symbol
- skor2 Nomenclature History
- Previous Names
-
- skor2 (1)
- zgc:153395
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and SMAD binding activity. Predicted to be involved in negative regulation of BMP signaling pathway and negative regulation of transcription by RNA polymerase II. Predicted to localize to nucleus and transcription regulator complex. Is expressed in spinal cord interneuron. Orthologous to human SKOR2 (SKI family transcriptional corepressor 2).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR003380 | SKI/SNO/DAC domain |
Domain | IPR014890 | c-SKI SMAD4-binding domain |
Family | IPR023216 | Transcription regulator SKI/SnoN |
Homologous_superfamily | IPR009061 | Putative DNA-binding domain superfamily |
Homologous_superfamily | IPR010919 | SAND-like domain superfamily |
Homologous_superfamily | IPR037000 | Ski-like, DNA-binding domain superfamily |
Domain Details Per Protein
Protein | Length | c-SKI SMAD4-binding domain | Putative DNA-binding domain superfamily | SAND-like domain superfamily | Ski-like, DNA-binding domain superfamily | SKI/SNO/DAC domain | Transcription regulator SKI/SnoN |
---|---|---|---|---|---|---|---|
UniProtKB:Q0P456
|
255 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available