FIGURE

FIGURE 3

ID

ZDB-FIG-221214-75

Publication

Liu et al., 2022 - Loxhd1b inhibits the hair cell development in zebrafish: Possible relation to the BDNF/TrkB/ERK pathway

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FIGURE 3

Morphology and number of hair cells and support cells in Loxhd1b-knockdown and control zebrafish. (A) Reduced numbers of neuromast hair cells in Loxhd1b-morphant fish labeled by FM1-43FX at 72 and 96 hpf. The arrows point to the position of posterior lateral line neuromasts. Scale bar = 300 ?m. (B,C) Immunostaining of zebrafish lateral line hair cells and support cells at 72 hpf. Hair cells are stained with myosin-7a antibody and support cells were stained with SOX2 antibody. Scale bar = 10 and 20 ?m. (D?G) Statistical analysis of the hair cell clusters in control and Loxhd1b-morphan based on t-test. ***P < 0.001 and ****P < 0.0001.

Expression Data

Antibody:	Ab4-myo7a
Fish:	WT AB + MO1-loxhd1b
Knockdown Reagent:	MO1-loxhd1b
Anatomical Term:	posterior lateral line neuromast neuromast hair cell
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-loxhd1b
Knockdown Reagent:	MO1-loxhd1b
Observed In:	posterior lateral line neuromast neuromast hair cell posterior lateral line neuromast neuromast support cell
Stage Range:	Protruding-mouth to Day 4

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Cell. Neurosci.