FIGURE

FIGURE 8

ID

ZDB-FIG-221214-80

Publication

Liu et al., 2022 - Loxhd1b inhibits the hair cell development in zebrafish: Possible relation to the BDNF/TrkB/ERK pathway

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FIGURE 8

The developmental defects of hair cells in Loxhd1b morphants rescued by BDNF mRNA. (A) Imaging analysis of control, Loxhd1b morphants, and rescued zebrafish at 72 hpf in bright field (right) and fluorescent field (left). Scale bar = 500 μm. (B) Imaging analysis of cristae hair cells in control, Loxhd1b morphants, and rescue group at 72 hpf. Scale bar = 50 μm. (C) Imaging analysis of support cells in control, Loxhd1b morphants, and rescue group at 72 hpf. Scale bar = 50 μm. (D) Quantification of the number of hair cell clusters in the posterior lateral line of different groups at 72 hpf. (E–G) Statistical analysis of the number of different hair cells and support cells in different groups at 72 hpf. ***P < 0.001 and ****P < 0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-loxhd1b
Knockdown Reagent:	MO1-loxhd1b
Observed In:	anterior crista auditory receptor cell lateral crista auditory receptor cell posterior crista auditory receptor cell posterior lateral line neuromast neuromast hair cell posterior lateral line neuromast neuromast support cell
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Cell. Neurosci.