FIGURE

Fig. 3

ID

ZDB-FIG-220922-36

Publication

Denans et al., 2022 - An anti-inflammatory activation sequence governs macrophage transcriptional dynamics during tissue injury in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

a Dot-Plot of selected differentially upregulated genes for each time point of the scRNA-seq time course within the effector population. b Representative confocal images (Maximum projection of a 200 μm z-stack) of an HCR-FISH for dusp1 in a 5dpf larvae (left) and zoom image of a representative neuromast (right) (from 6 whole larvae at 5dpf for homeostasis and 6 whole larvae at 5dpf after 15 min neo treatment. 2 biological replicates). c, e Representative confocal images (projection of a 30 μm z-stack) of HCR-FISH within the effector macrophages (arrows) for (c) il10ra, (e) fgl2a. d, f Quantifications of the percentage of HCR + effector macrophages (MΦ) for (d) il10ra, (f) fgl2a. (12 larvae with 3 neuromasts per larva and 3 biological replicates). For all graphs, data are represented as mean ± SD.

Expression Data

Genes:	dusp1 fgl2a il10ra
Fish:	gl22Tg
Condition:	chemical treatment by environment: neomycin
Anatomical Term:	neuromast macrophage
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	gl22Tg
Condition:	chemical treatment by environment: neomycin
Observed In:	macrophage interleukin-4-mediated signaling pathway macrophage interleukin-10-mediated signaling pathway macrophage obsolete glucocorticoid mediated signaling pathway macrophage polyamine biosynthetic process neuromast macrophage neuromast macrophage activation
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.