Gene

il10ra

ID
ZDB-GENE-070905-4
Name
interleukin 10 receptor, alpha
Symbol
il10ra Nomenclature History
Previous Names
  • IL10R1 (1)
  • crfb7 (1)
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Enables cytokine receptor activity. Predicted to be involved in cytokine-mediated signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Predicted to be integral component of membrane. Is expressed in gill; heart; liver; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in inflammatory bowel disease 28. Orthologous to human IL10RA (interleukin 10 receptor subunit alpha).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Grayfer et al., 2012
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Sunarto et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With il10ra Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
inflammatory bowel disease 28 Alliance Inflammatory bowel disease 28, early onset, autosomal recessive 613148
Associated With il10ra Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003961 Fibronectin type III
Domain IPR015373 Interferon/interleukin receptor domain
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036116 Fibronectin type III superfamily
Domain Details Per Protein
Protein Length Fibronectin type III Fibronectin type III superfamily Immunoglobulin-like fold Interferon/interleukin receptor domain
UniProtKB:A0FJI2 536
UniProtKB:A0A0R4ITC2 536
UniProtKB:A5PL67 308
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations