FIGURE

Fig. 1

ID

ZDB-FIG-220801-243

Publication

Eugenin von Bernhardi et al., 2022 - A versatile transcription factor: Multiple roles of orthopedia a (otpa) beyond its restricted localization in dopaminergic systems of developing and adult zebrafish (Danio rerio) brains

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

Sagittal overviews of the larval zebrafish brain (5 dpf; a,b) and the adult zebrafish basal diencephalon and hypothalamus (c-d). (a) is adapted from Herget et al. (2014) and highlights oxytocin cells (white arrows pointing to red cells) in the preoptic region among Otpa (green) immunopositive cells. (b) Drawing of this brain section shows additional Otpa domains (indicated in green, brain commissures in black), for example, in the intermediate nucleus of the ventral telencephalic area (Vi, interpreted as medial amygdala; adapted from Biechl et al., 2017), in the posterior tuberculum (PT), hypothalamus(Hy), and hindbrain (HB). (c/c1) shows a parasagittal adult section close to the midline stained for DAPI (c) and Otpa (c1) identifying some posterior tubercular and hypothalamic Otpa domains. (d/d1) shows a slightly more lateral parasagittal section (d; DAPI stained) highlighting posterior tubercular and hypothalamic catecholaminergic domains (d1; TH immunostained). Scale bars = 50 µm (a), 250 µm (c/d). Abbreviations: ac, anterior commissure; ATN, anterior tuberal nucleus; Ce, cerebellum; CM, corpus mamillare; d, dorsal; DIL, diffuse nucleus of hypothalamic inferior lobe; Ha, habenula; Hc-a, caudal zone of periventricular hypothalamus in front of a posterior recess; Hc-b, caudal zone of periventricular hypothalamus around posterior recess; Hv, ventral zone of periventricular hypothalamus; Hy, hypothalamus; LH, lateral hypothalamic nucleus; LR, lateral hypothalamic recess; NT, NeuroTrace; oc, optic chiasma; Oxt, oxytocin; pc, posterior commissure; Pit, pituitary; PM, magnocellular preoptic nucleus; Po (PO in panel A), preoptic region; poc, postoptic commissure; PPr, periventricular pretectum, PR, posterior hypothalamic recess; PT, posterior tuberculum; PTN, posterior tuberal nucleus; PVO, paraventricular organ; r, rostral; T, midbrain tegmentum; Tel, telencephalon; TeO, optic tectum; TPp, periventricular nucleus of posterior tuberculum; TPp-m, magnocellular cells of TPp; TPp-p, parvocellular cells of TPp; Vi, intermediate nucleus of ventral telencephalon

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Comp. Neurol.