FIGURE

Figure 6

ID

ZDB-FIG-220104-126

Publication

Li et al., 2021 - The Adaptor Protein Lurap1 Is Required for Cell Cohesion during Epiboly Movement in Zebrafish

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Figure 6

Disrupted cortical F-actin organization in the blastoderm of MZlurap1 mutant embryos. (a) Thin cortical F-actin belt is tightly organized in EVL cells of wild-type embryos. (b) Slightly diffuse and disrupted (arrows) cortical F-actin belt in EVL cells of MZlurap1 mutant embryos. (c) Loosely organized cortical F-actin in DEL cells of wild-type embryos. (d) Strongly diffuse and disrupted cortical F-actin in DEL cells of MZlurap1 mutant embryos. (e) Statistical analyses of cortical F-actin belt thickness. Data were obtained using 3 embryos from independent experiments in each condition. Numbers on the top of each column represent total cells examined in at least 3 embryos from different experiments. Bars represent the mean value � s.d. (****, p < 0.0001). (f) Regular localization of cortical �-catenin in EVL cells of wild-type embryos. (g) Disrupted and relatively diffuse localization of cortical �-catenin in EVL cells of MZlurap1 mutant embryos. (h) �-catenin localization in DEL cells of wild-type embryos. (i) Strongly disrupted �-catenin and diffuse localization in DEL cells of MZlurap1 mutant embryos. Scale bar: 20 �m.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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