FIGURE

Fig 1

ID

ZDB-FIG-210813-12

Publication

Gonçalves-Carneiro et al., 2021 - Origin and evolution of the zinc finger antiviral protein

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Fig 1

ZAP and PARP12 share a common ancestor.

(A) Schematic representation of the domain organization of human ZAP and its paralogues PARP12 and ZAP-like. (B) Diagrams of the organization of PARP12 (in yellow) and ZAP (in red) loci in vertebrate genomes generated using multiple genome browsers (NCBI, Ensembl, Genomicus). Evolutionary distance of the indicated species (presented in million years, Ma) is based on [36]. Chr, chromosome number. (C) Maximum likelihood tree (midpoint rooted) depicting phylogenetic relationships among PARP12- and ZAP-related genes in vertebrate and invertebrate species, generated with BEAST and 1000 bootstrap replicates. Shaded areas loosely clustered sequences from related species in the superclass Tetrapoda (in blue), clade Actinopterygii (Ray-finned fish, in green), the phylum Mollusca (molluscs, in yellow) and the phylum Cnidaria (in red).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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