FIGURE

Fig. 2

ID

ZDB-FIG-210405-2

Publication

Clark et al., 2021 - Complementary and divergent functions of zebrafish Tango1 and Ctage5 in tissue development and homeostasis

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Fig. 2

Craniofacial and other morphological defects in tango1 mutants are accentuated by ctage5 deletion. (A) Representative lateral (left) and ventral (right) images of Alcian blue–stained 4dpf larvae. (B) Representative images of plastic-sectioned and toluidine blue–stained 4dpf larvae cropped to show craniofacial alterations. TC = trabeculae, BC = buccal cavity, CH = ceratohyal cartilage. (C) Representative maximum intensity projection images showing TUNEL staining of 4dpf lens and sclera. (D) Representative images of plastic-sectioned and toluidine blue–stained 4dpf lens. (E) Representative images of lens dissected from 3-mo-old zebrafish. (F) Representative images showing ventricle-enriched cardiac myosin light chain (CMLC:GFP) expression. (G) Representative brightfield image of the trunk for each genotype. Arrowheads detail blood pooling in the caudal vein.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mia2^mw91/mw91 mia3^mw92/mw92 mia2^mw91/mw91; mia3^mw92/mw92
Observed In:	caudal vein cranial cartilage heart lens lens apoptotic process lens epithelium nucleate erythrocyte sclera apoptotic process
Stage Range:	Day 4 to Days 45-89

Phenotype Detail

Acknowledgments

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