FIGURE

Fig. 1

ID

ZDB-FIG-210405-1

Publication

Clark et al., 2021 - Complementary and divergent functions of zebrafish Tango1 and Ctage5 in tissue development and homeostasis

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Fig. 1

ctage5 and tango1 mutations affect size and survival of zebrafish: (A) Schematic showing CRISPR guide RNA cut sites (scissors) and the estimated final truncated proteins. (B) Representative brightfield images of all combinations of ctage5 and tango1 mutations in 4dpf zebrafish larvae. Y = yolk, SB = swim bladder, E = eye. (C) Length (one-way ANOVA, F = 38.6, p < 0.0001), (D) mass (one-way ANOVA, F = 28.22, p < 0.0001) and (E) survival (χ2 = 24.59, p < 0.05, n = 59) measurements of all combinations of ctage5 and tango1 mutant zebrafish at 2 mo raised in a low-density environment (about 10 fish per tank). Red-dotted lines in E represent expected survival, and black bars are actual survival. ** = p < 0.01, *** = p < 0.001, **** = p < 0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mia2^mw91/mw91 mia3^mw92/mw92 mia2^mw91/+ mia3^mw92/+ mia2^mw91/+; mia3^mw92/+ mia2^mw91/+; mia3^mw92/mw92 mia2^mw91/mw91; mia3^mw92/+ mia2^mw91/mw91; mia3^mw92/mw92
Observed In:	head mouth whole organism yolk
Stage Range:	Day 4 to Days 45-89

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Mol. Biol. Cell