Figure 4—figure supplement 2.

Change in advection pattern increases the time to PLD for earlier DAPT washout.

(A) Change in advection pattern at t = tg. The blue and red lines indicate the advection speed vd and strain rate, respectively. x-=x-xa where xa is the position of the anterior end of the PSM. (B), (C) Kymographs of vorticity for washout at (B) twash-out = 0 min (0 somite stage; ss) and (C) 270 min (9 ss). White dotted lines indicate tg at which the advection pattern changes (tg = 9 ss). Vorticity across the right PSM is shown. Trajectories of clockwise vortices for twash-out = 0 min and those of counter-clockwise vortices for twash-out = 270 min are presented. (D-G) Dependence of times to FRS (blue) and PLD (green) on washout time twash-out with change in advection pattern at (D) tg = 6 ss, (E) 9 ss, (F) 12 ss, and (G) 15 ss. The gray dotted lines indicate times to FRS and PLD for the constant tissue shown in Figure 4A in the main text. The box-whisker plot indicates (0.05, 0.25, 0.75, 0.95) quantiles of times to FRS and PLD for 100 realizations of simulations. The white bars indicate median.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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