ZFIN ID: ZDB-FIG-201009-15
Novoa et al., 2019 - Rag1 immunodeficiency-induced early aging and senescence in zebrafish are dependent on chronic inflammation and oxidative stress. Aging Cell   18(5):e13020 Full text @ Aging Cell
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Term:
Stage Range: Day 4 to Adult
PHENOTYPE:
Fish:
Observed In:
Stage Range: Day 4 to Adult

Graph Figure 1 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
acod1 WT standard conditions Day 4 whole organism RTPCR
Days 30-44 whole organism RTPCR
Adult whole organism RTPCR
rag1t26683/t26683 standard conditions Day 4 whole organism RTPCR
Days 30-44 whole organism RTPCR
Adult whole organism RTPCR
caspa WT standard conditions Day 4 whole organism RTPCR
Days 30-44 whole organism RTPCR
Adult whole organism RTPCR
rag1t26683/t26683 standard conditions Day 4 whole organism RTPCR
Days 30-44 whole organism RTPCR
Adult whole organism RTPCR
mxa WT standard conditions Day 4 whole organism RTPCR
Days 30-44 whole organism RTPCR
Adult whole organism RTPCR
rag1t26683/t26683 standard conditions Day 4 whole organism RTPCR
Days 30-44 whole organism RTPCR
Adult whole organism RTPCR
mxe WT standard conditions Day 4 whole organism RTPCR
Days 30-44 whole organism RTPCR
Adult whole organism RTPCR
rag1t26683/t26683 standard conditions Day 4 whole organism RTPCR
Days 30-44 whole organism RTPCR
Adult whole organism RTPCR
nlrp12l WT standard conditions Day 4 whole organism RTPCR
Days 30-44 whole organism RTPCR
Adult whole organism RTPCR
rag1t26683/t26683 standard conditions Day 4 whole organism RTPCR
Days 30-44 whole organism RTPCR
Adult whole organism RTPCR
prf1.2 WT standard conditions Day 4 whole organism RTPCR
Days 30-44 whole organism RTPCR
Adult whole organism RTPCR
rag1t26683/t26683 standard conditions Day 4 whole organism RTPCR
Days 30-44 whole organism RTPCR
Adult whole organism RTPCR
shisa10.2 WT standard conditions Day 4 whole organism RTPCR
Days 30-44 whole organism RTPCR
Adult whole organism RTPCR
rag1t26683/t26683 standard conditions Day 4 whole organism RTPCR
Days 30-44 whole organism RTPCR
Adult whole organism RTPCR
tnfrsf9a WT standard conditions Day 4 whole organism RTPCR
Days 30-44 whole organism RTPCR
Adult whole organism RTPCR
rag1t26683/t26683 standard conditions Day 4 whole organism RTPCR
Days 30-44 whole organism RTPCR
Adult whole organism RTPCR
trim35-14 WT standard conditions Day 4 whole organism RTPCR
Days 30-44 whole organism RTPCR
Adult whole organism RTPCR
rag1t26683/t26683 standard conditions Day 4 whole organism RTPCR
Days 30-44 whole organism RTPCR
Adult whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
rag1t26683/t26683 standard conditions Day 4 whole organism caspa expression increased amount, abnormal
Day 4 whole organism prf1.2 expression increased amount, abnormal
Day 4 whole organism shisa10.2 expression increased amount, abnormal
Days 30-44 whole organism acod1 expression increased amount, abnormal
Days 30-44 whole organism caspa expression increased amount, abnormal
Days 30-44 whole organism nlrp12l expression increased amount, abnormal
Days 30-44 whole organism prf1.2 expression increased amount, abnormal
Adult whole organism acod1 expression increased amount, abnormal
Adult whole organism caspa expression increased amount, abnormal
Adult whole organism mxa expression increased amount, abnormal
Adult whole organism mxe expression increased amount, abnormal
Adult whole organism nlrp12l expression increased amount, abnormal
Adult whole organism prf1.2 expression increased amount, abnormal
Adult whole organism shisa10.2 expression increased amount, abnormal
Adult whole organism tnfrsf9a expression increased amount, abnormal
Adult whole organism trim35-14 expression increased amount, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Aging Cell for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Aging Cell