Gene
tnfrsf9a
- ID
- ZDB-GENE-060421-8213
- Name
- tumor necrosis factor receptor superfamily, member 9a
- Symbol
- tnfrsf9a Nomenclature History
- Previous Names
-
- zgc:136557 (1)
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Predicted to enable signaling receptor activity. Predicted to be involved in regulation of cell population proliferation. Predicted to be located in membrane. Is expressed in cardiac ventricle and female organism. Human ortholog(s) of this gene implicated in immunodeficiency 109. Orthologous to human TNFRSF9 (TNF receptor superfamily member 9).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 109 | Alliance | Immunodeficiency 109 with lymphoproliferation | 620282 |
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Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | TNFR/NGFR cysteine-rich region | Tumor necrosis factor receptor 9, N-terminal, teleost |
|---|---|---|---|---|
| UniProtKB:E7F8V4 | InterPro | 285 | ||
| UniProtKB:A0A8M3AN45 | InterPro | 284 | ||
| UniProtKB:Q1RM18 | InterPro | 200 |
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| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tnfrsf9a-204
(1)
|
Ensembl | 999 nt | ||
| ncRNA |
tnfrsf9a-001
(1)
|
Ensembl | 1,353 nt | ||
| ncRNA |
tnfrsf9a-002
(1)
|
Ensembl | 875 nt | ||
| ncRNA |
tnfrsf9a-003
(1)
|
Ensembl | 723 nt |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-223I19 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:136557 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001040369 (1) | 1353 nt | ||
| Genomic | GenBank:BX663608 (1) | 190528 nt | ||
| Polypeptide | UniProtKB:E7F8V4 (1) | 285 aa |
- Koslow, M., Zhu, P., McCabe, C., Xu, X., Lin, X. (2023) Kidney transcriptome and cystic kidney disease genes in zebrafish. Frontiers in Physiology. 14:11840251184025
- Novoa, B., Pereiro, P., López-Muñoz, A., Varela, M., Forn-Cuní, G., Anchelin, M., Dios, S., Romero, A., Martinez-López, A., Medina-Gali, R.M., Collado, M., Coll, J., Estepa, A., Cayuela, M.L., Mulero, V., Figueras, A. (2019) Rag1 immunodeficiency-induced early aging and senescence in zebrafish are dependent on chronic inflammation and oxidative stress. Aging Cell. 18(5):e13020
- Kossack, M., Hein, S., Juergensen, L., Siragusa, M., Benz, A., Katus, H.A., Most, P., Hassel, D. (2017) Induction of cardiac dysfunction in developing and adult zebrafish by chronic isoproterenol stimulation. Journal of Molecular and Cellular Cardiology. 108:95-105
- Münch, J., Grivas, D., González-Rajal, Á., Torregrosa-Carrión, R., de la Pompa, J.L. (2017) Notch signalling restricts inflammation and serpine1 expression in the dynamic endocardium of the regenerating zebrafish heart.. Development (Cambridge, England). 144(8):1425-1440
- Ribas, L., Vanezis, K., Imués, M.A., Piferrer, F. (2017) Treatment with a DNA methyltransferase inhibitor feminizes zebrafish and induces long-term expression changes in the gonads. Epigenetics & chromatin. 10:59
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
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