mxe

ID

ZDB-GENE-030131-9609

Name

myxovirus (influenza virus) resistance E

Symbol

mxe Nomenclature History

Previous Names

wu:fj93f01
zgc:111895

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable GTPase activity and microtubule binding activity. Acts upstream of or within response to virus. Predicted to be located in presynapse. Predicted to be active in several cellular components, including microtubule; nucleus; and synapse. Is expressed in digestive system. Orthologous to human MX2 (MX dynamin like GTPase 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:111895 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mxe Human Ortholog

No data available

Associated With mxe Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019762	Dynamin, GTPase region, conserved site
Domain	IPR000375	Dynamin stalk domain
Domain	IPR001401	Dynamin, GTPase domain
Domain	IPR003130	Dynamin GTPase effector
Domain	IPR020850	GTPase effector domain
Domain	IPR030381	Dynamin-type guanine nucleotide-binding (G) domain
Domain	IPR045063	Dynamin, N-terminal
Family	IPR022812	Dynamin
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase