Gene

nlrp12l

ID
ZDB-GENE-090313-181
Name
NLR family pyrin domain containing 12-like
Symbol
nlrp12l Nomenclature History
Previous Names
  • si:dkey-126g1.6
  • si:dkey-126g1.7 (1)
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Human ortholog(s) of this gene implicated in CINCA Syndrome; Muckle-Wells syndrome; autosomal dominant nonsyndromic deafness 34; familial cold autoinflammatory syndrome (multiple); and urticaria. Orthologous to several human genes including NLRP12 (NLR family pyrin domain containing 12); NLRP13 (NLR family pyrin domain containing 13); and NLRP14 (NLR family pyrin domain containing 14).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Novoa et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nlrp12l Human Ortholog
No data available
Associated With nlrp12l Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR007111 NACHT nucleoside triphosphatase
Domain IPR029495 NACHT-associated domain
Domain IPR041075 NOD1/2, winged helix domain
Domain IPR041267 NACHT, LRR and PYD domains-containing protein, helical domain HD2
Family IPR051261 NOD-like receptor
1 - 5 of 8 Show all
Domain Details Per Protein
Protein Additional Resources Length Leucine-rich repeat Leucine-rich repeat domain superfamily NACHT-associated domain NACHT, LRR and PYD domains-containing protein, helical domain HD2 NACHT nucleoside triphosphatase NOD1/2, winged helix domain NOD-like receptor P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A8M6YXY0 InterPro 812
UniProtKB:A0A8M2B981 InterPro 1046
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Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA si:dkey-126g1.7-201 (1)
Ensembl
Ensembl 3,290 nt
ZFIN BLAST
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-126G1ZFIN Curated Data
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Sequences
Type Accession # Sequence Length (nt/aa) Analysis
RNARefSeq:XM_068216925 (1)4596 nt
ZFIN BLASTNCBI BLASTEnsemblUCSC BLAT
GenomicGenBank:BX927210 (1)175627 nt
MegaBLASTEnsembl
PolypeptideUniProtKB:A0A8M2B981 (1)1046 aa
ZFIN BLASTSIB BLASTEnsembl Protein Blast
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
TSV
1 - 2 of 2
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