ZFIN ID: ZDB-FIG-200107-15
Cai et al., 2018 - Ribosome biogenesis protein Urb2 regulates hematopoietic stem cells development via P53 pathway in zebrafish. Biochemical and Biophysical Research Communications   497(2):776-782 Full text @ Biochem. Biophys. Res. Commun.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage Range: Protruding-mouth to Day 4
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage Range: Protruding-mouth to Day 4

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
ccng1 urb2cq42/cq42 standard conditions Protruding-mouth caudal hematopoietic tissue ISH
cdkn1a urb2cq42/cq42 standard conditions Protruding-mouth caudal hematopoietic tissue ISH
mdm2 urb2cq42/cq42 standard conditions Protruding-mouth caudal hematopoietic tissue ISH
myb WT control Protruding-mouth caudal hematopoietic tissue ISH
WT + MO4-tp53 standard conditions Protruding-mouth caudal hematopoietic tissue ISH
tp53zdf1/zdf1 standard conditions Protruding-mouth caudal hematopoietic tissue ISH
tp53zdf1/zdf1 ; urb2cq42/cq42 standard conditions Protruding-mouth caudal hematopoietic tissue ISH
urb2cq42/cq42 standard conditions Protruding-mouth caudal hematopoietic tissue ISH
urb2cq42/cq42 + MO4-tp53 standard conditions Protruding-mouth caudal hematopoietic tissue ISH
rag1 WT standard conditions Day 4 thymus ISH
WT + MO4-tp53 standard conditions Day 4 thymus ISH
tp53zdf1/zdf1 standard conditions Day 4 thymus ISH
tp53zdf1/zdf1 ; urb2cq42/cq42 standard conditions Day 4 thymus ISH
urb2cq42/cq42 standard conditions Day 4 Not Detected thymus ISH
urb2cq42/cq42 + MO4-tp53 standard conditions Day 4 thymus ISH
tp53 urb2cq42/cq42 standard conditions Protruding-mouth caudal hematopoietic tissue ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
tp53zdf1/zdf1 ; urb2cq42/cq42 standard conditions Protruding-mouth caudal hematopoietic tissue myb expression amount, ameliorated
Day 4 thymus rag1 expression amount, ameliorated
urb2cq42/cq42 standard conditions Protruding-mouth caudal hematopoietic tissue ccng1 expression increased amount, abnormal
Protruding-mouth caudal hematopoietic tissue cdkn1a expression increased amount, abnormal
Protruding-mouth caudal hematopoietic tissue mdm2 expression increased amount, abnormal
Protruding-mouth caudal hematopoietic tissue myb expression decreased amount, abnormal
Protruding-mouth caudal hematopoietic tissue tp53 expression increased amount, abnormal
Day 4 thymus rag1 expression absent, abnormal
urb2cq42/cq42 + MO4-tp53 standard conditions Protruding-mouth caudal hematopoietic tissue myb expression amount, ameliorated
Day 4 thymus rag1 expression amount, ameliorated
Full text @ Biochem. Biophys. Res. Commun.