ZFIN ID: ZDB-FIG-191115-10
Bellesso et al., 2018 - FGF signaling deregulation is associated with early developmental skeletal defects in animal models for mucopolysaccharidosis type II (MPSII). Human molecular genetics   27:2262-2275 Full text @ Hum. Mol. Genet.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage Range: Long-pec to Adult
PHENOTYPE:
Fish:
Observed In:
Stage Range: Long-pec to Adult

Fig. 3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
d2EGFP idsia200/ia200 ; pt6Tg standard conditions Long-pec mandibular arch skeleton IFL
Long-pec otic vesicle IFL
Long-pec pharyngeal arch endoderm IFL
Long-pec trigeminal ganglion IFL
Long-pec whole organism RTPCR
pt6Tg control Long-pec mandibular arch skeleton IFL
Long-pec otic vesicle IFL
Long-pec pharyngeal arch endoderm IFL
Long-pec trigeminal ganglion IFL
Long-pec whole organism RTPCR
dusp6 WT control Adult fin RTPCR
Adult neurocranium RTPCR
Adult opercle RTPCR
idsia200/ia200 standard conditions Adult fin RTPCR
Adult neurocranium RTPCR
Adult opercle RTPCR
etv4 WT control Adult fin RTPCR
Adult neurocranium RTPCR
Adult opercle RTPCR
idsia200/ia200 standard conditions Adult fin RTPCR
Adult neurocranium RTPCR
Adult opercle RTPCR
idsia200/ia200 ; pt6Tg standard conditions Long-pec whole organism RTPCR
pt6Tg control Long-pec whole organism RTPCR
etv5b idsia200/ia200 ; pt6Tg standard conditions Long-pec whole organism RTPCR
pt6Tg control Long-pec whole organism RTPCR
mapk3 WT control Adult fin RTPCR
Adult neurocranium RTPCR
Adult opercle RTPCR
idsia200/ia200 standard conditions Adult fin RTPCR
Adult neurocranium RTPCR
Adult opercle RTPCR
idsia200/ia200 ; pt6Tg standard conditions Long-pec whole organism RTPCR
pt6Tg control Long-pec whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
idsia200/ia200 standard conditions Adult fin dusp6 expression decreased amount, abnormal
Adult fin etv4 expression decreased amount, abnormal
Adult fin mapk3 expression decreased amount, abnormal
Adult neurocranium dusp6 expression decreased amount, abnormal
Adult neurocranium etv4 expression decreased amount, abnormal
Adult neurocranium mapk3 expression decreased amount, abnormal
Adult opercle dusp6 expression decreased amount, abnormal
Adult opercle etv4 expression decreased amount, abnormal
Adult opercle mapk3 expression decreased amount, abnormal
idsia200/ia200 ; pt6Tg standard conditions Long-pec whole organism etv4 expression decreased amount, abnormal
Long-pec whole organism etv5b expression decreased amount, abnormal
Long-pec whole organism mapk3 expression decreased amount, abnormal
Long-pec whole organism d2EGFP expression decreased amount, abnormal
pt6Tg control Long-pec mandibular arch skeleton d2EGFP expression decreased amount, abnormal
Long-pec otic vesicle d2EGFP expression decreased amount, abnormal
Long-pec pharyngeal arch endoderm d2EGFP expression decreased amount, abnormal
Long-pec trigeminal ganglion d2EGFP expression decreased amount, abnormal
Full text @ Hum. Mol. Genet.