ZFIN Fish: pt6Tg

ZFIN ID: ZDB-FISH-150901-23954

Fish name:	pt6Tg
Genotype:	pt6Tg
Targeting Reagent:	none

HUMAN DISEASE MODELED by pt6Tg
No data available

GENE EXPRESSION
Gene expression in pt6Tg

RNA expression

Expressed Gene	Structure	Conditions	Figures
etv4	whole organism	control	Fig. 1, Fig. 3 from Bellesso et al., 2018
etv5b	whole organism	control	Fig. 1, Fig. 3 from Bellesso et al., 2018
mapk3	whole organism	control	Fig. 1, Fig. 3 from Bellesso et al., 2018

Protein expression

Antibody	Antigen Genes	Structure	Conditions	Figures
Ab1-tuba		Kupffer's vesicle cilium	control	FIGURE 3 from So et al., 2020
Ab2-aldh1a2		endocardium epicardium myocardium	physical alteration: anatomical structure, chemical treatment: dibenziodolium	Fig. 4 from Han et al., 2014
Ab1-mef2		myocardium	physical alteration: anatomical structure, chemical treatment: dibenziodolium	Fig. 4 from Han et al., 2014

Reporter gene expression

Expressed Gene	Structure	Conditions	Figures
d2EGFP	eye Kupffer's vesicle lens mandibular arch skeleton midbrain hindbrain boundary otic vesicle pharyngeal arch endoderm telencephalon trigeminal ganglion whole organism	standard conditions	FIGURE 3 from So et al., 2020 Fig. 12 from Vetrivel et al., 2019 Fig. 1, Fig. 3 from Bellesso et al., 2018
EGFP	anatomical structure anterior lateral plate mesoderm brain diencephalon dorsal region forerunner cell group hindbrain neural keel Kupffer's vesicle lens mandibular arch skeleton margin midbrain hindbrain boundary midbrain hindbrain boundary neural rod optic cup optic stalk otic vesicle pharyngeal arch pharyngeal endoderm presumptive neural retina presumptive rhombomere 3 presumptive rhombomere 4 rhombomere 4 shield solid lens vesicle spinal cord spinal cord neural tube tail bud trigeminal ganglion trigeminal placode whole organism postero-ventral region	standard conditions	Fig. 5 from Giuliodori et al., 2018 Fig. 1 from Anastasaki et al., 2012 Fig. 3 from Schneider et al., 2010 Fig. 10 from McMahon et al., 2009 Fig. 1 , Fig. 2 from Molina et al., 2007
	anatomical structure brain spinal cord spinal cord neural tube (not) tail bud	chemical treatment by environment: PD 0325901	Fig. 1 from Anastasaki et al., 2012
	endocardium epicardium	physical alteration: anatomical structure	Fig. 4 from Han et al., 2014

PHENOTYPE
Phenotype in pt6Tg

Phenotype	Conditions	Figures
anatomical structure EGFP expression decreased distribution, abnormal	chemical treatment by environment: PD 0325901	Fig. 1 from Anastasaki et al., 2012
brain EGFP expression decreased distribution, abnormal	chemical treatment by environment: PD 0325901	Fig. 1 from Anastasaki et al., 2012
mandibular arch skeleton d2EGFP expression decreased amount, abnormal	control	Fig. 3 from Bellesso et al., 2018
otic vesicle d2EGFP expression decreased amount, abnormal	control	Fig. 3 from Bellesso et al., 2018
pharyngeal arch endoderm d2EGFP expression decreased amount, abnormal	control	Fig. 3 from Bellesso et al., 2018
spinal cord EGFP expression decreased distribution, abnormal	chemical treatment by environment: PD 0325901	Fig. 1 from Anastasaki et al., 2012
spinal cord neural tube EGFP expression decreased distribution, abnormal	chemical treatment by environment: PD 0325901	Fig. 1 from Anastasaki et al., 2012
tail bud EGFP expression absent, abnormal	chemical treatment by environment: PD 0325901	Fig. 1 from Anastasaki et al., 2012
tail bud EGFP expression decreased distribution, abnormal	chemical treatment by environment: PD 0325901	Fig. 1 from Anastasaki et al., 2012
trigeminal ganglion d2EGFP expression decreased amount, abnormal	control	Fig. 3 from Bellesso et al., 2018

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