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General Information
ZIRC
ZFIN ID: ZDB-FIG-190923-23
Hübner et al., 2018 - Wnt/β-catenin signaling regulates VE-cadherin-mediated anastomosis of brain capillaries by counteracting S1pr1 signaling. Nature communications   9:4860 Full text @ Nat. Commun.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Antibody:
Fish:
Conditions:
Anatomical Term:
Stage Range: Prim-15 to High-pec
PHENOTYPE:
Fish:
Conditions:
Observed In:
Stage Range: Prim-15 to High-pec

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
axin2 rk8Tg; ubs3Tg chemical treatment by environment: IWR-1-endo Prim-25 brain vasculature blood vessel endothelial cell RTPCR
cdh5 rk8Tg; ubs3Tg chemical treatment by environment: IWR-1-endo Prim-25 brain vasculature blood vessel endothelial cell RTPCR
esama rk8Tg; ubs3Tg chemical treatment by environment: IWR-1-endo Prim-25 brain vasculature blood vessel endothelial cell RTPCR
lef1 rk8Tg; ubs3Tg chemical treatment by environment: IWR-1-endo Prim-25 brain vasculature blood vessel endothelial cell RTPCR
prickle1a rk8Tg; ubs3Tg chemical treatment by environment: IWR-1-endo Prim-25 brain vasculature blood vessel endothelial cell RTPCR
tcf15 rk8Tg; ubs3Tg chemical treatment by environment: IWR-1-endo Prim-25 brain vasculature blood vessel endothelial cell RTPCR
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-cdh5 IHC mu201Tg ; s843Tg heat shock Prim-15 brain vasculature blood vessel endothelial cell
IHC High-pec brain vasculature blood vessel endothelial cell
IHC s843Tg chemical treatment by environment: IWR-1-endo Prim-15 brain vasculature blood vessel endothelial cell
IHC High-pec brain vasculature blood vessel endothelial cell
Phenotype Details
Fish Conditions Stage Phenotype
mu201Tg ; s843Tg heat shock Prim-15 brain vasculature blood vessel endothelial cell ab1-cdh5 labeling increased amount, abnormal
High-pec brain vasculature blood vessel endothelial cell ab1-cdh5 labeling increased amount, abnormal
rk8Tg; ubs3Tg chemical treatment by environment: IWR-1-endo Prim-25 brain vasculature blood vessel endothelial cell axin2 expression decreased amount, abnormal
Prim-25 brain vasculature blood vessel endothelial cell lef1 expression decreased amount, abnormal
Prim-25 brain vasculature blood vessel endothelial cell prickle1a expression decreased amount, abnormal
Prim-25 brain vasculature blood vessel endothelial cell tcf15 expression decreased amount, abnormal
s843Tg chemical treatment by environment: IWR-1-endo Prim-15 brain vasculature blood vessel endothelial cell ab1-cdh5 labeling decreased amount, abnormal
High-pec brain vasculature blood vessel endothelial cell ab1-cdh5 labeling increased amount, abnormal
Full text @ Nat. Commun.