FIGURE

Fig. S1

ID

ZDB-FIG-181004-6

Publication

Wu et al., 2018 - Il34-Csf1r Pathway Regulates the Migration and Colonization of Microglial Precursors

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Fig. S1

Tg(Xla.Tubb:bcl-2) Transgene Successfully Blocks Neuronal Apoptosis in Most CNS Regions. Related to Figure 1.

(A and B) Whole mount Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay followed by transverse section showing representative images of apoptotic cells (red) (A) and quantification (B) of apoptotic cells in different CNS regions of 3 dpf WT or Tg(Xla.Tubb:bcl-2) embryos injected with pu.1 morpholino. n = 4 and 3 for WT and Tg(Xla.Tubb:bcl-2) embryos, respectively. Values represent means with SD. ns, P?0.05; ***, P ? 0.001; ****, P ? 0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	hkz013tTg + MO6-spi1b
Knockdown Reagent:	MO6-spi1b
Observed In:	optic tectum apoptotic process retina apoptotic process
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Cell, 46, Wu, S., Xue, R., Hassan, S., Nguyen, T.M.L., Wang, T., Pan, H., Xu, J., Liu, Q., Zhang, W., Wen, Z., Il34-Csf1r Pathway Regulates the Migration and Colonization of Microglial Precursors, 552-563.e4, Copyright (2018) with permission from Elsevier. Full text @ Dev. Cell