ZFIN ID: ZDB-FIG-181003-26
Yakulov et al., 2018 - CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury. Nature communications   9:3660 Full text @ Nat. Commun.
Anatomical Terms:
Stage Range: Prim-5 to Protruding-mouth
Observed In:
Stage: Long-pec

Fig. S7

myca expression in zebrafish embryos at 1-3 dpf, and up-regulation of myca in response to injury.

(a) myca was detected by in situ hybridization at 24 hpf in the zebrafish pronephros. Insert shows the posterior pronephros region close to the cloaca (c, cloaca). myca was strongly expressed in the head, the myotomes (arrow) and in the cloaca (magnification, c) at this stage. (b) Expression of myca was restricted to the head, the somatic furrow (arrow) and the pronephros (arrowheads) at 48 hpf. (c) Expression of myca in the somitic furrows declined at 72 hpf, but remained stable in the head, pronephros (arrowheads) and in the cloaca (c). (d) myca was up-regulated in the pronephric duct cells adjacent to a laser-induced wound at 48 hpf (magnification; c, cloaca) (Scale bars, 50 μm).

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
myca WT control Prim-5 cloaca ISH
Prim-5 head ISH
Prim-5 myotome ISH
Prim-5 pronephros ISH
Long-pec head ISH
Long-pec pronephros ISH
Long-pec somite border ISH
Protruding-mouth head ISH
Protruding-mouth pronephros ISH
WT light ablation: pronephros Long-pec pronephros ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT light ablation: pronephros Long-pec pronephros myca expression increased amount, abnormal
ZFIN wishes to thank the journal Nature communications for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Nat. Commun.