FIGURE

Fig. 4

ID
ZDB-FIG-180608-91
Publication
Paone et al., 2018 - Loss of zebrafish Smyd1a interferes with myofibrillar integrity without triggering the misfolded myosin response
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Fig. 4

Loss of Smyd1a does not trigger the misfolded myosin response. (A) ISH analysis of smyd1a expression in unc45b mutant embryos (steif) or embryos injected with a Cas9-protein/hsp90aa1-gRNA complex, respectively. (B) mRNA levels of the muscle chaperones unc45b and hsp90aa1 are strongly upregulated in muscle cells of fla mutants, whereas their expression is not affected by loss of smyd1a. (C) Rescue of fla mutants by injection of either smyd1a- or smyd1b-mRNA.

Expression Data
Genes:
Fish:
Knockdown Reagents:
Anatomical Term:
Stage: Protruding-mouth

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Observed In:
Stage: Protruding-mouth

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Biochem. Biophys. Res. Commun.