| ZFIN ID: ZDB-GENE-030131-9825 |
| Gene Name: | SET and MYND domain containing 1a | |||||||||||||
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| Gene Symbol: | smyd1a Nomenclature History |
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Attributions
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| Previous Names: | smyd1, sb:cb405, wu:fc09a05 | |||||||||||||
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| Gene Type: | protein_coding_gene | |||||||||||||
| Location: | Chr: 5 Mapping Details/Browsers | |||||||||||||
| Description: | Predicted to have histone-lysine N-methyltransferase activity. Involved in striated muscle cell development and thigmotaxis. Localizes to M band. Is expressed in fin; heart; musculature system; and somite. Orthologous to human SMYD1 (SET and MYND domain containing 1). | |||||||||||||
| Genome Resources: | Alliance (1), Gene:321245 (1), Ensembl(GRCz11):ENSDARG00000009280 (2) | |||||||||||||
| All Expression Data: | 26 figures from 8 publications |
| Directly Submitted Expression Data: | 5 figures (12 images) from Thisse et al., 2001 [cb405] |
| 12 figures (11 images) from Rauch et al., 2003 [fc09a05] | |
| Wild-type Stages, Structures: | Gastrula:Shield (6.0h-8.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) |
MUTATIONS AND SEQUENCE TARGETING REAGENTS
| Allele | Type | Localization | Consequence | Mutagen | Suppliers |
|---|---|---|---|---|---|
| mb4 | Small Deletion | Exon 3 | Frameshift, Premature Stop | CRISPR | |
| mb5 | Small Deletion | Exon 3 | Frameshift, Premature Stop | CRISPR | |
| sa31493 | Point Mutation | Unknown | Splice Site | ENU |
|
| sa40615 | Point Mutation | Unknown | Premature Stop | ENU |
|
Sequence Targeting Reagents
| Targeting Reagent | Created Alleles | Publications |
|---|---|---|
| CRISPR1-smyd1a | 2 | |
| CRISPR2-smyd1a |
|
1 |
| MO1-smyd1a | N/A | 2 |
| MO2-smyd1a | N/A | 2 |
| MO3-smyd1a | N/A | 1 |
| MO4-smyd1a | N/A | 1 |
| MO5-smyd1a | N/A | 1 |
PHENOTYPE
| Data: | 4 figures from 2 publications |
| Observed in: |
GENE ONTOLOGY
| Ontology | GO Term |
|---|---|
| Biological Process | sarcomere organization (more) |
| Cellular Component | M band (more) |
| Molecular Function | metal ion binding (more) |
| Type | Name | Length (nt) | Analysis | |
|---|---|---|---|---|
| mRNA |
smyd1a-202
(1)
|
1195 |
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|
| Browsers: UCSC, NCBI, Ensembl, ZFIN |
INTERACTIONS AND PATHWAYS
ANTIBODIES
No data available
PLASMIDS
No data available
CONSTRUCTS WITH SEQUENCES FROM smyd1a
| Construct | Regulatory Regions | Coding Sequences | Species | Tg Lines | Publications |
|---|---|---|---|---|---|
| Tg(unc45b:smyd1a-EGFP) | unc45b | EGFP, smyd1a | Danio rerio | 1 | 1 |
MARKER RELATIONSHIPS
| smyd1a Contained in: | [BAC] CH73-64K8 (1) |
| smyd1a Encodes: |
[EST]
cb405 (1) (order this),
fc09a05 (order this)
[cDNA] MGC:77936 (1) |
SEQUENCE INFORMATION
| Type | Accession # | Length (nt/aa) | Analysis |
|---|---|---|---|
| RNA | RefSeq:NM_205540 (1) | 1569 nt |
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| Genomic | GenBank:CU929062 (1) | 111698 nt | |
| Polypeptide | UniProtKB:Q6P0R5 (1) | 485 aa |
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ORTHOLOGY for smyd1a (
Chr:
5
)
CITATIONS (34)