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Ran et al., 2017 - Resveratrol ameliorates diet-induced dysregulation of lipid metabolism in zebrafish (Danio rerio). PLoS One   12:e0180865 Full text @ PLoS One
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Antibodies:
Fish:
Conditions:
Anatomical Term:
Stage: Adult
PHENOTYPE:
Fish:
Conditions:
Observed In:
Stage: Adult

Unillustrated author statements

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
pparg AB standard conditions Adult male organism muscle RTPCR
AB chemical treatment by diet: resveratrol Adult male organism muscle RTPCR
AB increased food availability Adult male organism muscle RTPCR
AB limited food availability Adult male organism muscle RTPCR
AB chemical treatment by diet: resveratrol, increased food availability Adult male organism muscle RTPCR
AB chemical treatment by diet: resveratrol, limited food availability Adult male organism muscle RTPCR
ppargc1a AB standard conditions Adult male organism muscle RTPCR
AB chemical treatment by diet: resveratrol Adult male organism muscle RTPCR
AB increased food availability Adult male organism muscle RTPCR
AB limited food availability Adult male organism muscle RTPCR
AB chemical treatment by diet: resveratrol, increased food availability Adult male organism muscle RTPCR
AB chemical treatment by diet: resveratrol, limited food availability Adult male organism muscle RTPCR
prkaa1 AB standard conditions Adult male organism muscle RTPCR
AB chemical treatment by diet: resveratrol Adult male organism muscle RTPCR
AB increased food availability Adult male organism muscle RTPCR
AB limited food availability Adult male organism muscle RTPCR
AB chemical treatment by diet: resveratrol, increased food availability Adult male organism muscle RTPCR
AB chemical treatment by diet: resveratrol, limited food availability Adult male organism muscle RTPCR
sirt1 AB standard conditions Adult male organism muscle RTPCR
AB chemical treatment by diet: resveratrol Adult male organism muscle RTPCR
AB increased food availability Adult male organism muscle RTPCR
AB limited food availability Adult male organism muscle RTPCR
AB chemical treatment by diet: resveratrol, increased food availability Adult male organism muscle RTPCR
AB chemical treatment by diet: resveratrol, limited food availability Adult male organism muscle RTPCR
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-prkaa1 WB AB standard conditions Adult male organism muscle
WB AB chemical treatment by diet: resveratrol Adult male organism muscle
WB AB increased food availability Adult male organism muscle
WB AB limited food availability Adult male organism muscle
WB AB chemical treatment by diet: resveratrol, increased food availability Adult male organism muscle
WB AB chemical treatment by diet: resveratrol, limited food availability Adult male organism muscle
Ab1-sirt1 WB AB standard conditions Adult male organism muscle
WB AB chemical treatment by diet: resveratrol Adult male organism muscle
WB AB increased food availability Adult male organism muscle
WB AB limited food availability Adult male organism muscle
WB AB chemical treatment by diet: resveratrol, increased food availability Adult male organism muscle
WB AB chemical treatment by diet: resveratrol, limited food availability Adult male organism muscle
Ab2-pparg WB AB standard conditions Adult male organism muscle
WB AB chemical treatment by diet: resveratrol Adult male organism muscle
WB AB increased food availability Adult male organism muscle
WB AB limited food availability Adult male organism muscle
WB AB chemical treatment by diet: resveratrol, increased food availability Adult male organism muscle
WB AB chemical treatment by diet: resveratrol, limited food availability Adult male organism muscle
Ab2-ppargc1a WB AB standard conditions Adult male organism muscle
WB AB chemical treatment by diet: resveratrol Adult male organism muscle
WB AB increased food availability Adult male organism muscle
WB AB limited food availability Adult male organism muscle
WB AB chemical treatment by diet: resveratrol, increased food availability Adult male organism muscle
WB AB chemical treatment by diet: resveratrol, limited food availability Adult male organism muscle
Ab3-cav1 WB AB standard conditions Adult male organism muscle
WB AB chemical treatment by diet: resveratrol Adult male organism muscle
WB AB increased food availability Adult male organism muscle
WB AB limited food availability Adult male organism muscle
WB AB chemical treatment by diet: resveratrol, increased food availability Adult male organism muscle
WB AB chemical treatment by diet: resveratrol, limited food availability Adult male organism muscle
Phenotype Details
Fish Conditions Stage Phenotype
AB chemical treatment by diet: resveratrol Adult blood cholesterol normal amount, normal
Adult blood glucose normal amount, normal
Adult blood triglyceride decreased amount, abnormal
Adult male organism increased length, abnormal
Adult male organism muscle Ab2-pparg labeling decreased amount, abnormal
Adult male organism muscle Ab3-cav1 labeling increased amount, abnormal
Adult male organism muscle pparg expression increased amount, abnormal
Adult male organism muscle sirt1 expression increased amount, abnormal
Adult muscle autophagy occurrence, normal
AB increased food availability Adult blood cholesterol increased amount, abnormal
Adult blood glucose increased amount, abnormal
Adult blood triglyceride normal amount, normal
Adult male organism increased length, abnormal
Adult male organism increased weight, abnormal
Adult male organism muscle prkaa1 expression decreased amount, abnormal
Adult male organism muscle Ab3-cav1 labeling increased amount, abnormal
Adult male organism muscle Ab2-pparg labeling increased amount, abnormal
Adult male organism muscle sirt1 expression increased amount, abnormal
Adult male organism muscle Ab1-sirt1 labeling increased amount, abnormal
Adult male organism muscle pparg expression increased amount, abnormal
Adult muscle autophagy occurrence, normal
AB limited food availability Adult blood triglyceride decreased amount, abnormal
Adult male organism decreased length, abnormal
Adult male organism decreased weight, abnormal
Adult male organism muscle Ab2-ppargc1a labeling increased amount, abnormal
Adult male organism muscle sirt1 expression increased amount, abnormal
Adult male organism muscle prkaa1 expression increased amount, abnormal
Adult male organism muscle Ab1-sirt1 labeling increased amount, abnormal
Adult male organism muscle pparg expression increased amount, abnormal
Adult male organism muscle Ab3-cav1 labeling increased amount, abnormal
Adult male organism muscle ppargc1a expression increased amount, abnormal
Adult muscle AMP-activated protein kinase activity increased occurrence, abnormal
Adult muscle autophagy increased occurrence, abnormal
AB chemical treatment by diet: resveratrol, increased food availability Adult blood cholesterol increased amount, ameliorated
Adult blood glucose increased amount, ameliorated
Adult blood triglyceride normal amount, normal
Adult male organism increased length, abnormal
Adult male organism increased weight, abnormal
Adult male organism muscle Ab3-cav1 labeling amount, ameliorated
Adult male organism muscle pparg expression decreased amount, abnormal
Adult male organism muscle prkaa1 expression decreased amount, abnormal
Adult male organism muscle Ab1-sirt1 labeling increased amount, abnormal
Adult male organism muscle sirt1 expression increased amount, abnormal
Adult muscle autophagy occurrence, ameliorated
AB chemical treatment by diet: resveratrol, limited food availability Adult blood cholesterol decreased amount, abnormal
Adult blood glucose decreased amount, abnormal
Adult blood triglyceride decreased amount, exacerbated
Adult male organism decreased length, abnormal
Adult male organism decreased weight, abnormal
Adult male organism muscle pparg expression increased amount, abnormal
Adult male organism muscle ppargc1a expression increased amount, abnormal
Adult male organism muscle Ab2-ppargc1a labeling increased amount, abnormal
Adult male organism muscle prkaa1 expression increased amount, abnormal
Adult male organism muscle Ab3-cav1 labeling increased amount, abnormal
Adult male organism muscle Ab1-sirt1 labeling increased amount, abnormal
Adult male organism muscle sirt1 expression increased amount, abnormal
Adult male organism muscle Ab2-pparg labeling increased amount, abnormal
Adult muscle AMP-activated protein kinase activity increased occurrence, abnormal
Adult muscle autophagy occurrence, ameliorated
Acknowledgments:
ZFIN wishes to thank the journal PLoS One for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS One