FIGURE

Fig. S5

ID

ZDB-FIG-171208-3

Publication

Lu et al., 2015 - Direct regulation of p53 by miR-142a-3p mediates the survival of hematopoietic stem and progenitor cells in zebrafish

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Fig. S5

Increased apoptosis in 142^C-/- embryos and upregulated expression of apoptotic genes upon knock down of miR-142a-3p.

(a) TUNEL assay displayed more apoptotic cells in the AGM region of 142^C-/- embryos. The number was quantified according to the TUNEL positive cells in the AGM region (mean±SD, n=3, *P<0.05). (b) Microarray analysis revealed that apoptotic genes represented by different colors of graph bar including trim50, p53, phlda3, caspase8, xrcc5, fas, sixx-35d8.1, and ypel3 were increased in the miR-142a-3p morphants at 2 and 4 dpf.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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