FIGURE

Fig. S2

ID

ZDB-FIG-171207-36

Publication

Lu et al., 2015 - Direct regulation of p53 by miR-142a-3p mediates the survival of hematopoietic stem and progenitor cells in zebrafish

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Fig. S2

Normal primitive hematopoiesis and vascular development in miR-142a knock out mutants.

(a) 142T^-/- embryos displayed normal expression of primitive hematopoiesis marker scl and erythrocyte marker gata1 by WISH at 24 hpf. Somitic marker myod served as control. (b) 142T^-/- embryos showed normal expression of primitive myeloid marker lyz and pu.1 by WISH at 24 and 36 hpf respectively. (c) Arterial marker dll4 dltC and efnb2a were unaffected in 142T^-/- embryos by WISH at 24 and 36 hpf respectively. (d) Venous marker flt4 and msr were unaffected in 142T^-/- embryos by WISH at 24 and 36 hpf respectively. (e) 142T^-/- embryos showed normal expression of dll4 and flt4 at 24 and 36 hpf by qPCR (mean±SD, n=3, ns stands for no significance).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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