FIGURE
Fig. S3
- ID
- ZDB-FIG-171208-1
- Publication
- Lu et al., 2015 - Direct regulation of p53 by miR-142a-3p mediates the survival of hematopoietic stem and progenitor cells in zebrafish
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Fig. S3
Defect of HSPC emergence is specifically caused by miR-142a-3p but not miR-142a-5p. (a) 142C-/- embryos showed decreased expression of HSPC marker runx1 at 26 and 36 hpf and cmyb at 36 hpf by WISH. (b) HSPC differentiated lineages showed reduction in 142C-/- embryos including erythrocytes (gata1), neutrophils (lyz) and lymphocytes (rag1) at 4 dpf by WISH. (c) MiR-142a-5p MO injected embryos displayed normal expression of HSC marker runx1 by WISH at 36 hpf. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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