FIGURE

Fig. 4

ID

ZDB-FIG-171004-11

Publication

Demy et al., 2017 - Trim33 / Tif1-? is essential for macrophage and neutrophil mobilisation to developmental or inflammatory cues

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Fig. 4

The basal migration in interstitial tissues of both macrophages and neutrophils is affected in moonshine mutants. In vivo 4D tracking of mCherry-positive macrophages and GFP-positive neutrophils in the head and anterior yolk sac area of mon^NQ039Tg(mpeg1:mCherryF; mpx:gfp) sibling (Sib) (A?A?) and mutant (Mut) (B?B?) embryos at 48?hpf. e, ear; l, lens; y, yolk sac; h, hindbrain; r, retina. Cell trajectories are shown in panels (A?,A?,B?,B?), with colour coding of speed (from 0 to 300?µm/h), and the number (Nb) of cells tracked per time point in each case is shown in C (as mean±s.d. for 80 time points). (D,E) Quantification of the mean±s.d. square displacement over time illustrates the migration defect of the mutant leukocytes.

Expression Data

Genes:	GFP mCherry
Fish:	i114Tg; ump2Tg trim33^{t30813/t30813}; i114Tg; ump2Tg
Anatomical Terms:	macrophage neutrophil
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	trim33^{t30813/t30813}; i114Tg; ump2Tg
Observed In:	macrophage macrophage migration neutrophil neutrophil migration
Stage:	Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Cell Sci.