FIGURE

Fig. 1

ID

ZDB-FIG-170206-16

Publication

Lu et al., 2017 - Tbx20 drives cardiac progenitor formation and cardiomyocyte proliferation in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 1

LA1110 mutants exhibit a reduction in cardiomyocyte cell number. (A and B) Tbx20 mutant embryos (B) form a thin and small heart tube at 26hpf compared with that of wild-type siblings (A), as indicated by the fluorescent labeling of differentiated cardiomyocytes by the myl7:EGFP transgene. (C and D) Wild type embryos display a looped two-chambered heart at 48hpf (C), whereas LA1110 mutant embryos (D) exhibit a thin, stretched and string-like heart. (E) Graph of the average number of GFP-positive cardiomyocytes in wild type and LA1110 mutant embryos at 30hpf (n=5). Error bars indicate standard deviations. Asterisks indicate a significant difference (**p<0.01).

Expression Data

Gene:	EGFP
Fish:	twu34Tg tbx20^{la1110/la1110}; twu34Tg
Anatomical Term:	cardiac muscle cell
Stage Range:	Prim-5 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	twu34Tg
Observed In:	cardiac muscle cell heart heart tube
Stage Range:	Prim-5 to Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 421(2), Lu, F., Langenbacher, A., Chen, J.N., Tbx20 drives cardiac progenitor formation and cardiomyocyte proliferation in zebrafish, 139-148, Copyright (2017) with permission from Elsevier. Full text @ Dev. Biol.