ZFIN Figure: Jin et al., 2016, Fig. 1

ZFIN ID: ZDB-FIG-161202-24

ZFIN ID: ZDB-FIG-161202-24

Jin et al., 2016 - cMyb acts in parallel and cooperatively with Cebp1 to regulate neutrophil maturation in zebrafish. Blood 128(3):415-26 Full text @ Blood

ADDITIONAL FIGURES

EXPRESSION / LABELING:

Genes:	apoeb cebp1 cybb GFP lyz mpx spi1b srgn
Fish:	WT myb^hkz3/hkz3 i114Tg myb^hkz3/hkz3 ; i114Tg
Anatomical Terms:	common myeloid progenitor microglial cell neutrophil neutrophil progenitor cell
Stage Range:	20-25 somites to Protruding-mouth

PHENOTYPE:

Fish:	myb^hkz3/hkz3 myb^hkz3/hkz3 ; i114Tg
Observed In:	neutrophil neutrophil granular vesicle neutrophil differentiation neutrophil progenitor cell
Stage Range:	Prim-25 to Protruding-mouth

Fig. 1 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details

Gene	Fish	Conditions	Stage	Qualifier	Anatomy	Assay
apoeb	WT	standard conditions	Protruding-mouth		microglial cell	ISH
	myb^hkz3/hkz3	standard conditions	Protruding-mouth		microglial cell	ISH
cebp1	WT	standard conditions	20-25 somites		neutrophil progenitor cell	ISH
	myb^hkz3/hkz3	standard conditions	20-25 somites		neutrophil progenitor cell	ISH
cybb	WT	standard conditions	Prim-25		neutrophil	ISH
	myb^hkz3/hkz3	standard conditions	Prim-25		neutrophil	ISH
GFP	i114Tg	standard conditions	Long-pec		neutrophil	IFL
	myb^hkz3/hkz3 ; i114Tg	standard conditions	Long-pec		neutrophil	IFL
lyz	WT	standard conditions	Prim-25		neutrophil	ISH
	myb^hkz3/hkz3	standard conditions	Prim-25	Not Detected	neutrophil	ISH
mpx	WT	standard conditions	Prim-25		neutrophil progenitor cell	ISH
	myb^hkz3/hkz3	standard conditions	Prim-25		neutrophil progenitor cell	ISH
spi1b	WT	standard conditions	20-25 somites		common myeloid progenitor	ISH
	myb^hkz3/hkz3	standard conditions	20-25 somites		common myeloid progenitor	ISH
srgn	WT	standard conditions	Prim-25		neutrophil	ISH
	myb^hkz3/hkz3	standard conditions	Prim-25		neutrophil	ISH

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
myb^hkz3/hkz3	standard conditions	Prim-25	neutrophil lyz expression absent, abnormal
		Prim-25	neutrophil srgn expression decreased amount, abnormal
		Prim-25	neutrophil granular vesicle decreased amount, abnormal
		Prim-25	neutrophil progenitor cell mpx expression decreased amount, abnormal
		Protruding-mouth	neutrophil differentiation decreased occurrence, abnormal
		Protruding-mouth	neutrophil immature, abnormal
myb^hkz3/hkz3 ; i114Tg	standard conditions	Long-pec	neutrophil granular vesicle decreased amount, abnormal

Full text @ Blood