FIGURE

Fig. 8

ID
ZDB-FIG-160927-26
Publication
Jim et al., 2016 - Infection of zebrafish embryos with live fluorescent Streptococcus pneumoniae as a real-time pneumococcal meningitis model
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Fig. 8

Time-lapse fluorescence imaging of Streptococcus pneumoniae-infected zebrafish embryos via the hindbrain ventricle at 2 days post fertilization. a-c Live fluorescence images of double-labelled Tg(mpx:GFP) i114 /Tg (mpeg1:mCherry) gl23 zebrafish embryos (green fluorescent neutrophils, red fluorescent macrophages). Dorsal view of the head region after injection with a PBS or b, c S. pneumoniae D39 with the corresponding Z-position (I) and bright-field image (II). Images b and c were acquired from the same zebrafish embryo at different positions. b (III) After injection of pneumococci in the hindbrain ventricle, green fluorescent neutrophils migrate in increasing numbers to the site of infection compared to a (III) PBS-injected zebrafish embryos. Macrophages were not observed in the subarachnoid space during b early pneumococcal infection of the hindbrain ventricle but c (III) remain localized in regions below the subarachnoid space. Scale bars, 100 µm
Expression Data
Genes:
Fish:
Condition:
Anatomical Terms:
Stage: Long-pec

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Condition:
Observed In:
Stage: Long-pec

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J Neuroinflammation
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