FIGURE

Fig. 4

ID

ZDB-FIG-151110-15

Publication

D'Aniello et al., 2015 - Rdh10a Provides a Conserved Critical Step in the Synthesis of Retinoic Acid during Zebrafish Embryogenesis

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4

Rdh10a depletion enhances defects in nls/aldh1a2 mutant embryos.

(A, D) WT control and Rdh10a deficient embryos. (B,E) Control and Rdh10a deficient embryos heterozygous for the nls allele. (C,F) Control and Rdh10a deficient embryos homozygous for the nls allele. Nls mutant embryos (C) show anteriorization of nervous system (black arrowhead), increases in the size of the head (black bracket), and pericardial edema. Rdh10a deficient; nls mutant embryos (F) have an accentuated anteriorization of the nervous system (arrowhead), larger and dysmorphic head (red bracket), and enhanced pericardial edema compared to nls embryos. Dorsal is up and anterior is to the right.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	aldh1a2^i26/i26 aldh1a2^i26/i26 + MO1-rdh10a + MO2-rdh10a + MO4-tp53
Knockdown Reagents:	MO1-rdh10a MO2-rdh10a MO4-tp53
Observed In:	head nervous system pericardium whole organism
Stage:	Long-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One