FIGURE

Fig. S3

ID
ZDB-FIG-151110-22
Publication
D'Aniello et al., 2015 - Rdh10a Provides a Conserved Critical Step in the Synthesis of Retinoic Acid during Zebrafish Embryogenesis
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Fig. S3

Rdh10a depletion enhances defects caused by inhibition of Aldh1a2.

(A) Control sibling embryo treated with DMSO. (B) Embryo treated with 0.05 µM DEAB (a suboptimal concentration) that has mild defects indicated of loss of RA signaling. (C) Rdh10a deficient embryo. (D) Rdh10a deficient embryos treated with the suboptimal concentration of DEAB results in an interaction that produces defects reminiscent of Rdh10a depleted nls mutant embryos (Fig 4). The head is enlarged (brackets) and the border between the hindbrain and anterior spinal cord is accentuated (arrow), indicating the hindbrain is anteriorized.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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