FIGURE

Fig. 11

ID

ZDB-FIG-151019-18

Publication

Sztal et al., 2015 - Zebrafish models for nemaline myopathy reveal a spectrum of nemaline bodies contributing to reduced muscle function

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Fig. 11

Functional analysis of Actc1b knockdown in zebrafish. a Brightfield images of wild-type embryos injected with actc1b targeting morpholinos (MO) compared to control uninjected embryos. b Quantification of the maximum acceleration recorded from touch-evoked response assays of Actc1b morphants compared to control zebrafish at 2 dpf. Error bars represent SEM for three replicate experiments (20 fish per replicate), **p < 0.01. c Quantification of the distance traveled by Actc1b morphants compared to control zebrafish at 6 dpf. Error bars represent ±SEM for three replicate experiments (n = 48 per experiment), **p < 0.01

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-actc1b WT + MO2-actc1b
Knockdown Reagents:	MO1-actc1b MO2-actc1b
Observed In:	swimming thigmotaxis
Stage Range:	Long-pec to Day 6

Phenotype Detail

Acknowledgments

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