FIGURE

Fig. 1

ID

ZDB-FIG-150526-14

Publication

Burrows et al., 2015 - An In Vivo Requirement for the Mediator Subunit Med14 in the Maintenance of Stem Cell Populations

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Fig. 1

Characterization of the log Mutant Phenotype

(A–I) Expression of cardiac markers in (WT) and log mutant (MUT) embryos. While at 1.0 dpf the linear heart tube (black arrowhead) was apparent in all embryos (“WT/MUT”), at 2.25 dpf log mutant hearts were unlooped, with the ventricle directly above the atrium (yellow and red arrowheads, respectively).

(J–M) At 4.0 dpf, semicircular canals in the otic vesicles (black arrow heads in J and K) and elongation of the pectoral fins (black arrowheads in L and M) were absent in mutant embryos.

(N) Change in head/trunk angle over time in WT and mutant embryos (10 WT and 20 mutants measured per time point).

See also Figure S1.

Expression Data

Genes:	myh6 myh7 myl7
Fish:	WT med14^s231/s231
Anatomical Terms:	atrium cardiac ventricle heart heart tube presumptive atrium heart tube presumptive cardiac ventricle heart tube
Stage Range:	Prim-5 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	med14^s231/s231
Observed In:	embryonic organ development heart looping heart tube inner ear pectoral fin semicircular canal
Stage Range:	Prim-5 to Day 4

Phenotype Detail

Acknowledgments

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