FIGURE

Fig. 2

ID

ZDB-FIG-150413-16

Publication

Zhou et al., 2015 - UXT potentiates angiogenesis by attenuating Notch signaling

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Fig. 2

UXT is essential for zebrafish angiogenesis. (A-C) RT-PCR verification of angiogenesis markers in 18hpf, 24hpf or 30hpf zebrafish embryos injected with 4ng of control morpholino (Ctrl MO) or with 4ng of UXT morpholino (UXT MO). Data shown are the mean±s.e.m. (at least three independent experiments); *P<0.05, **P<0.01 versus the corresponding control. (D) Whole-mount in situ hybridization of embryos injected with 4ng of control morpholino (Ctrl MO) or 4ng of UXT morpholino (UXT MO). Riboprobes against the angiogenesis marker kdrl, the pronephric marker pax2.1 and the erythroid marker gata1 were visualized at 22hpf. The red arrowhead indicates the decreased expression of kdrl in UXT-deficient embryos.

Expression Data

Genes:	angpt1 flt1 kdrl myod1 nes pax2a ptgs2a
Fish:	AB AB + MO2-uxt
Knockdown Reagent:	MO2-uxt
Anatomical Terms:	pronephros trunk vasculature vasculature whole organism
Stage Range:	26+ somites to Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO2-uxt
Knockdown Reagent:	MO2-uxt
Observed In:	trunk vasculature whole organism
Stage Range:	26+ somites to Prim-15

Phenotype Detail

Acknowledgments

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