Gene
ptgs2a
- ID
- ZDB-GENE-020530-2
- Name
- prostaglandin-endoperoxide synthase 2a
- Symbol
- ptgs2a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Exhibits peroxidase activity. Involved in animal organ development; cellular response to organic cyclic compound; and response to steroid hormone. Human ortholog(s) of this gene implicated in several diseases, including Barrett's esophagus; artery disease (multiple); arthritis (multiple); liver disease (multiple); and lung disease (multiple). Is expressed in several structures, including cardiovascular system; digestive system; endoderm; gonad; and head. Orthologous to human PTGS2 (prostaglandin-endoperoxide synthase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 39 figures from 32 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | EGF-like domain | Haem peroxidase, animal-type | Haem peroxidase domain superfamily, animal type | Haem peroxidase superfamily | Oxylipin biosynthesis and metabolism |
|---|---|---|---|---|---|---|
|
UniProtKB:Q8JH43
|
601 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ptgs2a-201
(1)
|
Ensembl | 2,135 nt | ||
| ncRNA |
ptgs2a-002
(1)
|
Ensembl | 673 nt |
Interactions and Pathways
No data available
Plasmids
No data available