FIGURE

Fig. 6

ID

ZDB-FIG-141230-25

Publication

Amacher et al., 2002 - The zebrafish T-box genes no tail and spadetail are required for development of trunk and tail mesoderm and medial floor plate

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Fig. 6

The nodal-related gene cyclops (cyc) is not required for medial floor plate development in the absence of spt function. sonic hedgehog (shh) expression in trunk medial floor plate (MFP) of wild-type (A) and mutant (B-D) embryos at 24 hpf. As noted already, spt^– MFP is often broader and some MFP cells are located ventral to the notochord (arrow) (C). In contrast, MFP is completely absent in the trunk of cyc^– embryos (B), but is significantly restored in spt^–;cyc^– embryos (D). Ventral brain shh expression in spt^–;cyc^– embryos is comparable to that in cyc^– embryos (data not shown); thus, suppression of the cyc^– MFP defect by the spt mutation is restricted to the trunk and tail. Lateral views, with anterior to the left. Scale bar: 100 μm.

Expression Data

Gene:	shha
Fish:	WT tbx16^b104/b104 Df(Chr12:hhex,ndr2)b16/b16 tbx16^b104/b104; Df(Chr12:hhex,ndr2)b16/b16
Anatomical Term:	medial floor plate
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	tbx16^b104/b104 Df(Chr12:hhex,ndr2)b16/b16
Observed In:	medial floor plate medial floor plate cell
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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