FIGURE

Fig. 6

ID

ZDB-FIG-140919-14

Publication

Ordas et al., 2013 - MicroRNA-146 function in the innate immune transcriptome response of zebrafish embryos to Salmonella typhimurium infection

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Fig. 6

Increased infection-induction of apolipoprotein gene expression under conditions of combined miR-146a and miR-146b knockdown. (A-F) Embryos were injected with control morpholino (scMO) or with a combination of 146aMO1 and 146bMO1 (146a/bMOs) and infected with S. typhimurium as described in Figure 5. Gene expression levels of six apolipoprotein genes, apoa1a (A), apoa4 (B), apoba (C), apobb (D), apoc1l (E), and apoeb (F), were analyzed by qPCR in two replicate infection experiments (1 and 2) and relative expression levels are shown with the lowest expression level set at 1. Data are the mean ± SEM of triplicate qPCR measurements. Asterisks indicate significant differences (*, P < 0.05; **, P <0.01) determined by an un-paired t-test.

Expression Data

Genes:	apoa1a apoa4b.1 apoba apobb.1 apoc1 apoeb
Fish:	AB/TL AB/TL + MO1-dre-mir-146b-1 + MO3-mir146a
Condition:	bacterial treatment: Salmonella enterica subsp. enterica serovar Typhimurium
Knockdown Reagents:	MO1-dre-mir-146b-1 MO3-mir146a
Anatomical Term:	whole organism
Stage Range:	Prim-5 to Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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